7 comments

  • Dylan16807 1 minute ago
    > The problem is that the gap between a medicinal dose and a toxic dose is very small

    What's this claim based on? I don't think it's the rat study linked nearby. I looked through it and they didn't really compare doses.

    If it's a linear effect on dropping blood pressure, that seems like an overblown way to talk about it. If it's something else, I'd love to hear more.

  • NDlurker 39 minutes ago
    Old Vice documentary about it. This is where I had first heard about it. Used to be really hard to find the honey online, like only one or 2 places that sold it

    https://youtu.be/wDOvmhqvIA8

    • phoronixrly 1 minute ago
      Thank you! I couldn't make myself read this entire LLM-generated article.
  • nkrisc 25 minutes ago
    They mention the toxin comes from the rhododendron flower. I remember camping in North Carolina once and one of the people I was with warned against burning anything from the rhododendron in the area, as supposedly the smoke would give you the runs.

    I mostly thought they were joking, and I have no idea what specific type of rhododendron would be there (if any), but maybe there’s a glimmer of merit to it? Or maybe they were thinking of a different plant?

    This was somewhere in the Blue Ridge Mountains, if I remember correctly.

    • john_strinlai 8 minutes ago
      i believe ingestion is the primary concern, but the smoke can also lead to symptoms, yes.
  • AngryData 23 minutes ago
    If you buy psychoactive honey/drugs online, it is on you to find out what it is and what kind of dosage you should take.
    • Dylan16807 8 minutes ago
      It's on you to figure out the dosage you can take, and it should be on the producer to label the dosage they're selling.
      • mcmcmc 5 minutes ago
        [delayed]
    • Forgeties79 20 minutes ago
      Yes but also we need to deal with the reality of the world, which is 1) not everyone is going to and 2) they don’t deserve to die because of it.
      • sokoloff 13 minutes ago
        I agree they don’t “deserve” to die, but someone comfortable with that level of risk management is quite hard to fully protect from themselves.
        • Forgeties79 4 minutes ago
          Most OD’s and such with drugs happens when someone trusts someone. They don’t just pick them up off the ground and go town. It’s basically the whole idea behind food safety.
  • daedrdev 36 minutes ago
    I imagine the native also built up tolerance over generations, not just knowledge as the article contends . Dying from a specific action is quite the evolutionary motivator
    • culi 30 minutes ago
      As with many psychoactive plants and foods, the adaptation here isn't so much a genetic/physiological tolerance as it is an often in-depth body of knowledge/practices for how to utilize the drug/medicine safely. Look at the notorious Datura for example which can cause you to go into a delirious state for over 2 days. The amount of preparation, processing, and knowledge that goes into administering it safely is lost on modern day kids who simply read an Erowid experience about a powerful psychoactive plant that likely grows locally.
      • Loughla 4 minutes ago
        Datura is fucking dangerous. Deliriants are no joke in general. That one in particular is really dangerous because it grows absolutely anywhere and is very easy to identify.

        Source; chemistry was my favorite class in high school and college because it helped me understand how to extract what I wanted from plants like jimsonweed and Mimosa trees.

        Also no one should do that.

  • mock-possum 9 minutes ago
    Metta Beshay, my new favorite drug explainer, has a neat video on the subject: https://youtu.be/5X3dCBQYdek
  • meindnoch 25 minutes ago
    A lot of things sold online can stop your heart.
    • nozzlegear 22 minutes ago
      A reasonable person wouldn't expect honey to stop their heart though.
    • rootsudo 11 minutes ago
      Exactly, thank you.
    • Bang2Bay 24 minutes ago
      Name a few. I want to be an informed person.
      • Supermancho 17 minutes ago
        * Sibutramine (weight loss medication)

        * Suldenafil or tadalafil (ED medication)

        * SARMS (steroids in general)

        * Caffeine powder (another game of guess the dosage)

      • emdash 6 minutes ago
        Water (in the right dosage)
      • drop_star 14 minutes ago
        Yohimbine is popular for weightloss but its dangerous if not dosed correctly